Studies on antitumor polysaccharides, especially D-II, from mycelium of Coriolus versicolor.
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چکیده
منابع مشابه
Antitumor effects of a refined polysaccharide peptide fraction isolated from Coriolus versicolor: in vitro and in vivo studies.
RPSP, a refined polysaccharide peptide fraction isolated by fast performance liquid chromatography (FPLC) from the crude powder of total peptide-bound polysaccharides of cultivated Coriolus versicolor Cov-1 dose-dependently inhibited the proliferation of a human hepatoma cell line (HEPG2). The effective dose causing 50% inhibition following 3-day exposure to RPSP was 243 +/- 36 micrograms/ml fo...
متن کاملPurification, characterization, and antitumor activity of a novel glucan from the fruiting bodies of Coriolus Versicolor
Cancer is one of the most common causes of deaths worldwide. Herein, we report an efficient natural anticancer glucan (CVG) extracted from Coriolus Versicolar (CV). CVG was extracted by the hot water extraction method followed by ethanol precipitation and purified using gas exclusion chromatography. Structural analysis revealed that CVG has a linear α-glucan chain composed of only (1→ 6)-α-D-Gl...
متن کاملCoriolus versicolor extracts: relevance in cancer management
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متن کاملPolysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production.
The protein-bound polysaccharides or polysaccharopeptides produced by Coriolus versicolor are effective immunopotentiators, which are used to supplement the chemotherapy and radiotherapy of cancers and various infectious diseases. Antitumor activity of polysaccharopeptides has been documented. Several kinds of protein-bound polysaccharides have been shown to be produced by the white rot fungus,...
متن کاملEffects of β-glucans from Coriolus versicolor on Macrophage Functions in Young and Aged mice
The immune system may play an important role in aging and the changes in the immune status are associated with treatment of various immunomodulators. This study examined the effects of β-glucans isolated from mushroom fungi, Coriolus versicolor on macrophages functions in young (8-weeks-old) and aged (82-weeks-old) male C57BL/6 mice. When peritoneal macrophages were treated with various concent...
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ژورنال
عنوان ژورنال: The Japanese Journal of Pharmacology
سال: 1980
ISSN: 0021-5198,1347-3506
DOI: 10.1254/jjp.30.503